Sex Differences in Coronary Artery Disease and Diabetes Revealed by scRNA-Seq and CITE-Seq of Human CD4+ T Cells

Despite the decades-old knowledge that males and people with diabetes mellitus (DM) are at increased risk for coronary artery disease (CAD), the reasons for this association are only partially understood. Among the immune cells involved, recent evidence supports a critical role of T cells as drivers...

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Main Authors: Ryosuke Saigusa, Jenifer Vallejo, Rishab Gulati, Sujit Silas Armstrong Suthahar, Vasantika Suryawanshi, Ahmad Alimadadi, Jeffrey Makings, Christopher P. Durant, Antoine Freuchet, Payel Roy, Yanal Ghosheh, William Pandori, Tanyaporn Pattarabanjird, Fabrizio Drago, Angela Taylor, Coleen A. McNamara, Avishai Shemesh, Lewis L. Lanier, Catherine C. Hedrick, Klaus Ley
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/17/9875