Comprehensive Lipidome Profiling of the Kidney in Early-Stage Diabetic Nephropathy

Comprehensive Lipidome Profiling of the Kidney in Early-Stage Diabetic Nephropathy

Metabolic changes associated with diabetes are reported to lead to the onset of early-stage diabetic nephropathy (DN). Furthermore, lipotoxicity is implicated in renal dysfunction. Most studies of DN have focused on a single or limited number of lipids, and the lipidome of the kidney during early-st...

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Bibliographic Details
Main Authors: Biyu Hou, Ping He, Peng Ma, Xinyu Yang, Chunyang Xu, Sin Man Lam, Guanghou Shui, Xiuying Yang, Li Zhang, Guifen Qiang, Guanhua Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Endocrinology
Subjects:
diabetic nephropathy
lipidomics
glomerular filtration barrier
lipotoxicity
sphingolipids
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00359/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2020.00359/full

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