Discovery and Anti-Inflammatory Activity of a Cyanobacterial Fatty Acid Targeting the Keap1/Nrf2 Pathway

Discovery and Anti-Inflammatory Activity of a Cyanobacterial Fatty Acid Targeting the Keap1/Nrf2 Pathway

The monounsaturated fatty acid 7(<i>E</i>)-9-keto-hexadec-7-enoic acid (<b>1</b>) and three structurally related analogues with different oxidation states and degrees of unsaturation (<b>2</b>–<b>4</b>) were discovered from a marine benthic cyanobacter...

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Bibliographic Details
Main Authors: Fatma H. Al-Awadhi, Emily F. Simon, Na Liu, Ranjala Ratnayake, Valerie J. Paul, Hendrik Luesch
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Marine Drugs
Subjects:
marine cyanobacteria
fatty acids
inflammation
RNA sequencing
NF-κB
immune function
Online Access:https://www.mdpi.com/1660-3397/21/11/553

Internet

https://www.mdpi.com/1660-3397/21/11/553

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