Development of a Mucoadhesive Vehicle Based on Lyophilized Liposomes for Drug Delivery through the Sublingual Mucosa

Development of a Mucoadhesive Vehicle Based on Lyophilized Liposomes for Drug Delivery through the Sublingual Mucosa

A pharmaceutical vehicle based on lyophilized liposomes is proposed for the buccal administration of drugs aimed at systemic delivery through the sublingual mucosa. Liposomes made of egg phosphatidylcholine and cholesterol (7/3 molar ratio) were prepared and lyophilized in the presence of different...

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Bibliographic Details
Main Authors: María José De Jesús Valle, Aranzazu Zarzuelo Castañeda, Cristina Maderuelo, Alejandro Cencerrado Treviño, Jorge Loureiro, Paula Coutinho, Amparo Sánchez Navarro
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceutics
Subjects:
liposomes
transmucosal delivery
lyophilized liposomes
liposome permeation
sublingual tablets
Online Access:https://www.mdpi.com/1999-4923/14/7/1497

Internet

https://www.mdpi.com/1999-4923/14/7/1497

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