Robust Glycoproteomics Platform Reveals a Tetra‐Antennary Site‐Specific Glycan Capping with Sialyl‐Lewis Antigen for Early Detection of Gastric Cancer

Robust Glycoproteomics Platform Reveals a Tetra‐Antennary Site‐Specific Glycan Capping with Sialyl‐Lewis Antigen for Early Detection of Gastric Cancer

Abstract The lack of efficient biomarkers for the early detection of gastric cancer (GC) contributes to its high mortality rate, so it is crucial to discover novel diagnostic targets for GC. Recent studies have implicated the potential of site‐specific glycans in cancer diagnosis, yet it is challeng...

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Bibliographic Details
Main Authors: Luyao Liu, Lei Liu, Yan Wang, Zheng Fang, Yangyang Bian, Wenyao Zhang, Zhongyu Wang, Xianchun Gao, Changrui Zhao, Miaomiao Tian, Xiaoyan Liu, Hongqiang Qin, Zhimou Guo, Xinmiao Liang, Mingming Dong, Yongzhan Nie, Mingliang Ye
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Advanced Science
Subjects:
gastric cancer
intact glycopeptides
MS‐based glycoproteomics
serum biomarkers
site‐specific N‐glycans
Online Access:https://doi.org/10.1002/advs.202306955

Internet

https://doi.org/10.1002/advs.202306955

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