7β-(3-Ethyl-<i>cis</i>-crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-<i>Z</i> Notonipetranone Attenuates Neuropathic Pain by Suppressing Oxidative Stress, Inflammatory and Pro-Apoptotic Protein Expressions

7β-(3-Ethyl-<i>cis</i>-crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-<i>Z</i> Notonipetranone Attenuates Neuropathic Pain by Suppressing Oxidative Stress, Inflammatory and Pro-Apoptotic Protein Expressions

7β-(3-Ethyl-<i>cis</i>-crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-<i>Z</i>-notonipetranone (ECN), a sesquiterpenoid obtained from a natural source has proved to be effective in minimizing various side effects associated with opioids and nonsteroidal anti-inflammatory...

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Bibliographic Details
Main Authors: Amna Khan, Adnan Khan, Sidra Khalid, Bushra Shal, Eunwoo Kang, Hwaryeong Lee, Geoffroy Laumet, Eun Kyoung Seo, Salman Khan
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
neuropathic markers
anti-neuroinflammation
ECN
myelin sheath
DNA disruption
Online Access:https://www.mdpi.com/1420-3049/26/1/181

Internet

https://www.mdpi.com/1420-3049/26/1/181

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