Identification of Novel Drug Candidate for Epithelial Ovarian Cancer via In Silico Investigation and In Vitro Validation

Identification of Novel Drug Candidate for Epithelial Ovarian Cancer via In Silico Investigation and In Vitro Validation

Epithelial ovarian cancer (EOC) has a poor prognosis and high mortality rate; patients are easy to relapse with standard therapies. So, there is an urgent need to develop novel drugs. In this study, differentially expressed genes (DEGs) of EOC were identified in The Cancer Genome Atlas (TCGA) and Ge...

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Bibliographic Details
Main Authors: Dan Zou, Jin Bai, Enting Lu, Chunjiao Yang, Jiaqing Liu, Zhenpeng Wen, Xuqin Liu, Zi Jin, Mengdan Xu, Lei Jiang, Ye Zhang, Yi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
epithelial ovarian cancer
CDK1
piperlongumine
molecular docking
cell cycle
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.745590/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.745590/full

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