Gremlin 1 blocks vascular endothelial growth factor signaling in the pulmonary microvascular endothelium
The bone morphogenetic protein (BMP) antagonist gremlin 1 plays a central role in the pathogenesis of hypoxic pulmonary hypertension (HPH). Recently, non-canonical functions of gremlin 1 have been identified, including specific binding to the vascular endothelial growth factor receptor-2 (VEGFR2). W...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-03-01
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| Series: | Pulmonary Circulation |
| Online Access: | https://doi.org/10.1177/2045894018807205 |