Chromatographic reversed HPLC and TLC-densitometry methods for simultaneous determination of serdexmethylphenidate and dexmethylphenidate in presence of their degradation products—with computational assessment

Chromatographic reversed HPLC and TLC-densitometry methods for simultaneous determination of serdexmethylphenidate and dexmethylphenidate in presence of their degradation products—with computational assessment

Abstract Two Chromatographic methods have been established and optimized for simultaneous determination of serdexmethylphenidate (SER.DMP) and dexmethylphenidate (DMP) in the presence of their degradation products. The first method is a reversed phase high performance liquid chromatography with diod...

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Bibliographic Details
Main Authors: Khadiga M. Kelani, Ahmed M. W. Nassar, Gamal A. Omran, Samir Morshedy, Ahmed Elsonbaty, Wael Talaat
Format: Article
Language:English
Published: BMC 2023-07-01
Series:BMC Chemistry
Subjects:
Serdexmethylphenidate (SER.DMP)
Dexmethylphenidate (DMP)
HPLC–DAD
TLC-densitometry
SER.DMP and DMP degradation products
Molecular dynamic simulation
Online Access:https://doi.org/10.1186/s13065-023-00986-3

Internet

https://doi.org/10.1186/s13065-023-00986-3

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