Respiratory Microbiome Profiling for Etiologic Diagnosis of Pneumonia in Mechanically Ventilated Patients

Respiratory Microbiome Profiling for Etiologic Diagnosis of Pneumonia in Mechanically Ventilated Patients

Etiologic diagnosis of bacterial pneumonia relies on identification of causative pathogens by cultures, which require extended incubation periods and have limited sensitivity. Next-generation sequencing of microbial DNA directly from patient samples may improve diagnostic accuracy for guiding antibi...

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Bibliographic Details
Main Authors: Georgios D. Kitsios, Adam Fitch, Dimitris V. Manatakis, Sarah F. Rapport, Kelvin Li, Shulin Qin, Joseph Huwe, Yingze Zhang, Yohei Doi, John Evankovich, William Bain, Janet S. Lee, Barbara Methé, Panayiotis V. Benos, Alison Morris, Bryan J. McVerry
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Microbiology
Subjects:
microbiome
pneumonia
16S rRNA gene sequencing
respiratory failure
antibiotic stewardship
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01413/full

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https://www.frontiersin.org/article/10.3389/fmicb.2018.01413/full

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