Alpha-synuclein suppression by targeted small interfering RNA in the primate substantia nigra.
The protein alpha-synuclein is involved in the pathogenesis of Parkinson's disease and other neurodegenerative disorders. Its toxic potential appears to be enhanced by increased protein expression, providing a compelling rationale for therapeutic strategies aimed at reducing neuronal alpha-synu...
| Glavni autori: | , , , , , |
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| Format: | Članak |
| Jezik: | English |
| Izdano: |
Public Library of Science (PLoS)
2010-01-01
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| Serija: | PLoS ONE |
| Online pristup: | http://europepmc.org/articles/PMC2920329?pdf=render |