Pro-inflammatory feedback loops define immune responses to pathogenic Lentivirus infection

Pro-inflammatory feedback loops define immune responses to pathogenic Lentivirus infection

Abstract Background The Lentivirus human immunodeficiency virus (HIV) causes chronic inflammation and AIDS in humans, with variable rates of disease progression between individuals driven by both host and viral factors. Similarly, simian lentiviruses vary in their pathogenicity based on characterist...

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Bibliographic Details
Main Authors: Aaron J. Wilk, Joshua O. Marceau, Samuel W. Kazer, Ira Fleming, Vincent N. Miao, Jennyfer Galvez-Reyes, Jason T. Kimata, Alex K. Shalek, Susan Holmes, Julie Overbaugh, Catherine A. Blish
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Genome Medicine
Subjects:
Lentiviruses
Single-cell transcriptomics
Cell-cell communication
Online Access:https://doi.org/10.1186/s13073-024-01290-y

Internet

https://doi.org/10.1186/s13073-024-01290-y

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