K121Q polymorphism in the Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 gene is associated with acute kidney rejection.

The identification of risk factors for acute rejection (AR) may lead to strategies to improve success of kidney transplantation. Ectonucleotidases are ectoenzymes that hydrolyze extracellular nucleotides into nucleosides, modulating the purinergic signaling. Some members of the Ectonucleotidase fami...

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Bibliographic Details
Main Authors: Denise A Sortica, Daisy Crispim, Andrea C Bauer, Pamela S Nique, Bruna B Nicoletto, Ricieli P Crestani, Jennifer T Staehler, Roberto C Manfro, Luis H Canani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219062