Smad7 in the hippocampus contributes to memory impairment in aged mice after anesthesia and surgery

Smad7 in the hippocampus contributes to memory impairment in aged mice after anesthesia and surgery

Abstract Background Postoperative cognitive dysfunction (POCD) is a common neurological complication following anesthesia and surgery. Increasing evidence has demonstrated that neuroinflammation caused by systemic inflammatory responses during the perioperative period is a key factor in the occurren...

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Bibliographic Details
Main Authors: Changliang Liu, Jiahui Wu, Ming Li, Rui Gao, Xueying Zhang, Shixin Ye-Lehmann, Jiangning Song, Tao Zhu, Chan Chen
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Journal of Neuroinflammation
Subjects:
Postoperative cognitive dysfunction
Smad7
TGF-β
Inflammation
Apoptosis
Online Access:https://doi.org/10.1186/s12974-023-02849-z

Internet

https://doi.org/10.1186/s12974-023-02849-z

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