Challenges of driving CD30-directed CAR-T cells to the clinic

Abstract Chimeric antigen receptor T (CAR-T) cells are a promising new treatment for patients with relapsed or refractory hematologic malignancies, including lymphoma. Given the success of CAR-T cells directed against CD19, new targets are being developed and tested, since not all lymphomas express...

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Bibliographic Details
Main Authors: Natalie S. Grover, Barbara Savoldo
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-019-5415-9