Circulating Small Extracellular Vesicle-Derived miR-342-5p Ameliorates Beta-Amyloid Formation via Targeting Beta-site APP Cleaving Enzyme 1 in Alzheimer’s Disease

Circulating Small Extracellular Vesicle-Derived miR-342-5p Ameliorates Beta-Amyloid Formation via Targeting Beta-site APP Cleaving Enzyme 1 in Alzheimer’s Disease

Alzheimer’s disease (AD) is a common neurodegenerative disorder with progressive cognitive impairment in the elderly. Beta-amyloid (Aβ) formation and its accumulation in the brain constitute one of the pathological hallmarks of AD. Until now, how to modulate Aβ formation in hippocampal neurons remai...

Full description

Bibliographic Details
Main Authors: Zhiwu Dong, Hongjun Gu, Qiang Guo, Xianglu Liu, Feifei Li, Huiling Liu, Li Sun, Huimin Ma, Kewen Zhao
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
extracellular vesicle
miRNA
Alzheimer’s disease
BACE1
amyloid-beta
neurons
Online Access:https://www.mdpi.com/2073-4409/11/23/3830

Internet

https://www.mdpi.com/2073-4409/11/23/3830

Similar Items