Specific regulation of mechanical nociception by Gβ5 involves GABA-B receptors

Specific regulation of mechanical nociception by Gβ5 involves GABA-B receptors

Mechanical, thermal, and chemical pain sensation is conveyed by primary nociceptors, a subset of sensory afferent neurons. The intracellular regulation of the primary nociceptive signal is an area of active study. We report here the discovery of a Gβ5-dependent regulatory pathway within mechanical n...

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Bibliographic Details
Main Authors: Mritunjay Pandey, Jian-Hua Zhang, Poorni R. Adikaram, Claire Kittock, Nicole Lue, Adam Awe, Katherine Degner, Nirmal Jacob, Jenna Staples, Rachel Thomas, Allison B. Kohnen, Sundar Ganesan, Juraj Kabat, Ching-Kang Chen, William F. Simonds
Format: Article
Language:English
Published: American Society for Clinical investigation 2023-07-01
Series:JCI Insight
Subjects:
Neuroscience
Online Access:https://doi.org/10.1172/jci.insight.134685

Internet

https://doi.org/10.1172/jci.insight.134685

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