Inhibitor of Hyaluronic Acid Synthesis 4-Methylumbelliferone Suppresses the Secretory Processes That Ensure the Invasion of Neutrophils into Tissues and Induce Inflammation

Integrin-dependent adhesion of neutrophils to tissue, accompanied by the development of neutrophil-induced inflammation, occurs both in the focus of infection and in the absence of infection in metabolic disorders such as reperfusion after ischemia, diabetes mellitus, or the development of pneumonia...

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Main Authors: Svetlana I. Galkina, Natalia V. Fedorova, Alexander L. Ksenofontov, Ekaterina A. Golenkina, Marina V. Serebryakova, Vladimir I. Stadnichuk, Ludmila A. Baratova, Galina F. Sud’ina
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/10/2/314