The Initial Gut Microbiota and Response to Antibiotic Perturbation Influence <named-content content-type="genus-species">Clostridioides difficile</named-content> Clearance in Mice

ABSTRACT The gut microbiota has a key role in determining susceptibility to Clostridioides difficile infections (CDIs). However, much of the mechanistic work examining CDIs in mouse models uses animals obtained from a single source. We treated mice from 6 sources (2 University of Michigan colonies a...

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Bibliographic Details
Main Authors: Sarah Tomkovich, Joshua M. A. Stough, Lucas Bishop, Patrick D. Schloss
Format: Article
Language:English
Published: American Society for Microbiology 2020-10-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00869-20