Substance P Antagonism Prevents Chemotherapy-Induced Cardiotoxicity

<i>Background</i>: Doxorubicin (DOX), used in chemotherapeutic regimens in many cancers, has been known to induce, cardiotoxicity and life-threatening heart failure or acute coronary syndromes in some patients. We determined the role of Substance P (SP), a neuropeptide and its high affin...

Full description

Bibliographic Details
Main Authors: Ashiq Legi, Emma Rodriguez, Thomas K. Eckols, Cyrus Mistry, Prema Robinson
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/7/1732