Tissue engineering approaches to develop decellularized tendon matrices functionalized with progenitor cells cultured under undifferentiated and tenogenic conditions

Tissue engineering approaches to develop decellularized tendon matrices functionalized with progenitor cells cultured under undifferentiated and tenogenic conditions

Tendon ruptures and retractions with an extensive tissue loss represent a major clinical problem and a great challenge in surgical reconstruction. Traditional approaches consist in autologous or allogeneic grafts, which still have some drawbacks. Hence, tissue engineering strategies aimed at develop...

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Bibliographic Details
Main Authors: Daniele D’Arrigo, Marta Bottagisio, Silvia Lopa, Matteo Moretti, Arianna B. Lovati
Format: Article
Language:English
Published: AIMS Press 2017-11-01
Series:AIMS Bioengineering
Subjects:
decellularized tendon
undifferentiated mesenchymal stem cells (U-MSCs)
extracellular matrix
type I collagen
tenogenic differentiation (T-MSCs)
functionalized tendon constructs
cell repopulation and static culture
Online Access:http://www.aimspress.com/Bioengineering/article/1717/fulltext.html

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http://www.aimspress.com/Bioengineering/article/1717/fulltext.html

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