Anti-MDA5 Antibody Linking COVID-19, Type I Interferon, and Autoimmunity: A Case Report and Systematic Literature Review

Anti-MDA5 Antibody Linking COVID-19, Type I Interferon, and Autoimmunity: A Case Report and Systematic Literature Review

IntroductionThe SARS-CoV-2 infection has been advocated as an environmental trigger for autoimmune diseases, and a paradigmatic example comes from similarities between COVID-19 and the myositis-spectrum disease associated with antibodies against the melanoma differentiation antigen 5 (MDA5) in terms...

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Bibliographic Details
Main Authors: Antonio Tonutti, Francesca Motta, Angela Ceribelli, Natasa Isailovic, Carlo Selmi, Maria De Santis
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
COVID-19
type I interferon signature
anti-MDA5 syndrome
inflammatory myositis
immunology
autoimmune disease
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.937667/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.937667/full

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