Natamycin interferes with ergosterol-dependent lipid phases in model membranes

Natamycin interferes with ergosterol-dependent lipid phases in model membranes

Natamycin is an antifungal polyene macrolide that is used as a food preservative but also to treat fungal keratitis and other yeast infections. In contrast to other polyene antimycotics, natamycin does not form ion pores in the plasma membrane, but its mode of action is poorly understood. Using nucl...

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Bibliographic Details
Main Authors: Vibeke Akkerman, Holger A. Scheidt, Peter Reinholdt, Mohammad Bashawat, Maria Szomek, Max Lehmann, Pablo Wessig, Douglas F. Covey, Jacob Kongsted, Peter Müller, Daniel Wüstner
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:BBA Advances
Subjects:
Polyene macrolide
Yeast
Antifungals
Ergosterol
Cholesterol
Lipid phase
Online Access:http://www.sciencedirect.com/science/article/pii/S2667160323000315

Internet

http://www.sciencedirect.com/science/article/pii/S2667160323000315

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