Alanyl-tRNA Synthetase Quality Control Prevents Global Dysregulation of the <named-content content-type="genus-species">Escherichia coli</named-content> Proteome

ABSTRACT Mechanisms have evolved to prevent errors in replication, transcription, and translation of genetic material, with translational errors occurring most frequently. Errors in protein synthesis can occur at two steps, during tRNA aminoacylation and ribosome decoding. Recent advances in protein...

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Bibliographic Details
Main Authors: Paul Kelly, Nicholas Backes, Kyle Mohler, Christopher Buser, Arundhati Kavoor, Jesse Rinehart, Gregory Phillips, Michael Ibba
Format: Article
Language:English
Published: American Society for Microbiology 2019-12-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.02921-19