Advancing age and the rs6265 BDNF SNP are permissive to graft-induced dyskinesias in parkinsonian rats
Abstract The rs6265 single nucleotide polymorphism (SNP) in the gene for brain-derived neurotrophic factor is a common variant that alters therapeutic outcomes for individuals with Parkinson’s disease (PD). We previously investigated the effects of this SNP on the experimental therapeutic approach o...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-08-01
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Series: | npj Parkinson's Disease |
Online Access: | https://doi.org/10.1038/s41531-024-00771-6 |