The low affinity neurotrophin receptor CD271 regulates phenotype switching in melanoma
The aggressive nature of melanoma cells relies on their ability to switch from a high-proliferative/low-invasive to a low-proliferative/high-invasive state; however, the mechanisms governing this switch are unclear. Here, using in vivo models of human melanoma, the authors show that CD271 is a key r...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-12-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-01573-6 |