alpha-Globin genes: thalassemic and structural alterations in a Brazilian population

alpha-Globin genes: thalassemic and structural alterations in a Brazilian population

Seven unrelated patients with hemoglobin (Hb) H disease and 27 individuals with alpha-chain structural alterations were studied to identify the alpha-globin gene mutations present in the population of Southeast Brazil. The -alpha3.7, --MED and -(alpha)20.5 deletions were investigated by PCR, whereas...

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Autori principali: M.R.S.C. Wenning, E.M. Kimura, F.F. Costa, S.T.O. Saad, S. Gervásio, S.B. de Jorge, E. Borges, N.M. Silva, M.F. Sonati
Natura: Articolo
Lingua:English
Pubblicazione: Associação Brasileira de Divulgação Científica 2000-09-01
Serie:Brazilian Journal of Medical and Biological Research
Soggetti:
alpha-globin genes
alpha-globin structural variants
alpha-thalassemia
hemoglobin H
Hb H disease
hemoglobin variants
hemoglobinopathies
Accesso online:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000900008

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000900008

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