Glyoxalase 2: Towards a Broader View of the Second Player of the Glyoxalase System

Glyoxalase 2: Towards a Broader View of the Second Player of the Glyoxalase System

Glyoxalase 2 is a mitochondrial and cytoplasmic protein belonging to the metallo-β-lactamase family encoded by the hydroxyacylglutathione hydrolase (HAGH) gene. This enzyme is the second enzyme of the glyoxalase system that is responsible for detoxification of the α-ketothaldehyde methylglyoxal in c...

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Bibliographic Details
Main Authors: Andrea Scirè, Laura Cianfruglia, Cristina Minnelli, Brenda Romaldi, Emiliano Laudadio, Roberta Galeazzi, Cinzia Antognelli, Tatiana Armeni
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Antioxidants
Subjects:
glyoxalase system
glutathione
methylglyoxal
post-translational modification (PTM)
metallo beta-lactamase
Online Access:https://www.mdpi.com/2076-3921/11/11/2131

Internet

https://www.mdpi.com/2076-3921/11/11/2131

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