Decoding the mechanism of Eleutheroside E in treating osteoporosis via network pharmacological analysis and molecular docking of osteoclast-related genes and gut microbiota

Decoding the mechanism of Eleutheroside E in treating osteoporosis via network pharmacological analysis and molecular docking of osteoclast-related genes and gut microbiota

ObjectiveEleutheroside E (EE) is an anti-inflammatory natural compound derived from the edible medicinal herb Acanthopanax senticosus. This study aims to investigate the underlying mechanism of the anti-osteoporosis action of EE through network pharmacology, molecular docking and gut microbiota.Mate...

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Bibliographic Details
Main Authors: Tianyu Zhou, Yilin Zhou, Dongdong Ge, Youhong Xie, Jiangyan Wang, Lin Tang, Qunwei Dong, Ping Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Endocrinology
Subjects:
Eleutheroside E (EE)
postmenopausal osteoporosis (PMO)
network pharmacology
molecular docking
gut microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1257298/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1257298/full

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