miR-139-5p Loss-Mediated WTAP Activation Contributes to Hepatocellular Carcinoma Progression by Promoting the Epithelial to Mesenchymal Transition

miR-139-5p Loss-Mediated WTAP Activation Contributes to Hepatocellular Carcinoma Progression by Promoting the Epithelial to Mesenchymal Transition

Background: Hepatocellular carcinoma (HCC) is a primary aggressive gastrointestinal neoplasm that affects patients worldwide. It has been shown that Wilms' tumor 1-associating protein (WTAP) is frequently upregulated in various cancers. However, the potential role of WTAP in HCC remains largely...

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Bibliographic Details
Main Authors: Wenli Liu, Xuewei Gao, Xiaolong Chen, Na Zhao, Ying Sun, Yawen Zou, Yize Guan, Lin Yang, Xiaoxian Pei, Guozhen Wang, Bin Wang, Mingcheng Li, Wengang Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
WTAP
metastasis
HCC
epithelial to mesenchymal transition
miR-139-5p
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.611544/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.611544/full

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