Combination of auraptene and arsenic trioxide induces apoptosis and cellular accumulation in the subG1 phase in adult T-cell leukemia cells

Objective(s): Despite advances in the treatment of adult T-cell leukemia/lymphoma (ATLL), the survival rate of this malignancy remains significantly low. Auraptene (AUR) is a natural coumarin with broad-spectrum anticancer activities. To introduce a more effective therapeutic strategy for ATLL, we i...

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Bibliographic Details
Main Authors: Mohaddeseh Kazemi, Hamideh Kouhpeikar, Zahra Delbari, Faeze Khodadadi, Sina Gerayli, Mehrdad Iranshahi, Arman Mosavat, Fatemeh Rassouli, Houshang RafatPanah
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2021-12-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_19143_365db23fa9b32ee3ac683c2cbef6499b.pdf