Inhibition of TRAF6 improves hyperlipidemic acute pancreatitis by alleviating pyroptosis in vitro and in vivo rat models

Inhibition of TRAF6 improves hyperlipidemic acute pancreatitis by alleviating pyroptosis in vitro and in vivo rat models

Abstract Objective Hypertriglyceridemia (HTG) is one of the common causes of acute pancreatitis (AP). Hyperlipidemic acute pancreatitis (HTG-AP) is associated with higher mortality owing to its tendency for greater severity and rapid progression. The purpose of this study was to explore the mechanis...

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Bibliographic Details
Main Authors: Biwei Wei, Zhou Su, Huiying Yang, Yong Feng, Chunmei Meng, Zhihai Liang
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Biology Direct
Subjects:
Hyperlipidemic acute pancreatitis
Tumor necrosis factor receptor-related factor 6
Pyroptosis
Cysteinyl aspartate specific proteinase-1
Gasdermin D
Online Access:https://doi.org/10.1186/s13062-023-00380-y

Internet

https://doi.org/10.1186/s13062-023-00380-y

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