An observational human study investigating the effect of anabolic androgenic steroid use on the transcriptome of skeletal muscle and whole blood using RNA-Seq

An observational human study investigating the effect of anabolic androgenic steroid use on the transcriptome of skeletal muscle and whole blood using RNA-Seq

Abstract Background The effects of Anabolic Androgenic Steroids (AAS) are largely illustrated through Androgen Receptor induced gene transcription, yet RNA-Seq has yet to be conducted on human whole blood and skeletal muscle. Investigating the transcriptional signature of AAS in blood may aid AAS de...

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Bibliographic Details
Main Authors: Alexander Kolliari-Turner, Giscard Lima, Guan Wang, Fernanda Rossell Malinsky, Antonia Karanikolou, Gregor Eichhorn, Kumpei Tanisawa, Jonathan Ospina-Betancurt, Blair Hamilton, Paulette Y.O. Kumi, Jonathan Shurlock, Vasileios Skiadas, Richard Twycross-Lewis, Liam Kilduff, Renan Paulo Martin, Garrett I. Ash, Cynthia Potter, Fergus M. Guppy, Jane T. Seto, Chiara Fossati, Fabio Pigozzi, Paolo Borrione, Yannis Pitsiladis
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Medical Genomics
Subjects:
Anabolic androgenic steroids
Doping
Skeletal muscle
Whole blood
RNA-Seq
Gene expression
Online Access:https://doi.org/10.1186/s12920-023-01512-z

Internet

https://doi.org/10.1186/s12920-023-01512-z

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