Preloaded D-methionine protects from steady state and impulse noise-induced hearing loss and induces long-term cochlear and endogenous antioxidant effects

<h4>Objective</h4> Determine effective preloading timepoints for D-methionine (D-met) otoprotection from steady state or impulse noise and impact on cochlear and serum antioxidant measures. <h4>Design</h4> D-met started 2.0-, 2.5-, 3.0-, or 3.5- days before steady-state or im...

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Bibliographic Details
Main Authors: Kathleen Campbell, Nicole Cosenza, Robert Meech, Michael Buhnerkempe, Jun Qin, Leonard Rybak, Daniel Fox
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654202/?tool=EBI