Prolonged contact with dendritic cells turns lymph node‐resident NK cells into anti‐tumor effectors

Prolonged contact with dendritic cells turns lymph node‐resident NK cells into anti‐tumor effectors

Abstract Natural killer (NK) cells are critical players against tumors. The outcome of anti‐tumor vaccination protocols depends on the efficiency of NK‐cell activation, and efforts are constantly made to manipulate them for immunotherapeutic approaches. Thus, a better understanding of NK‐cell activa...

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Bibliographic Details
Main Authors: Francesca Mingozzi, Roberto Spreafico, Tatiana Gorletta, Clara Cigni, Marco Di Gioia, Michele Caccia, Laura Sironi, Maddalena Collini, Matias Soncini, Michela Rusconi, Ulrich H von Andrian, Giuseppe Chirico, Ivan Zanoni, Francesca Granucci
Format: Article
Language:English
Published: Springer Nature 2016-09-01
Series:EMBO Molecular Medicine
Subjects:
dendritic cells
immunosurveillance
innate immunity
natural killer cells
two‐photon microscopy
Online Access:https://doi.org/10.15252/emmm.201506164

Internet

https://doi.org/10.15252/emmm.201506164

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