A small protein coded within the mitochondrial canonical gene nd4 regulates mitochondrial bioenergetics

A small protein coded within the mitochondrial canonical gene nd4 regulates mitochondrial bioenergetics

Abstract Background Mitochondria have a central role in cellular functions, aging, and in certain diseases. They possess their own genome, a vestige of their bacterial ancestor. Over the course of evolution, most of the genes of the ancestor have been lost or transferred to the nucleus. In humans, t...

Full description

Bibliographic Details
Main Authors: Laura Kienzle, Stefano Bettinazzi, Thierry Choquette, Marie Brunet, Hajar Hosseini Khorami, Jean-François Jacques, Mathilde Moreau, Xavier Roucou, Christian R. Landry, Annie Angers, Sophie Breton
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Biology
Subjects:
Mitochondria
Mitogenome
Alternative open reading frame
Mitochondrial proteome
Protein coding potential
nd4
Online Access:https://doi.org/10.1186/s12915-023-01609-y

Internet

https://doi.org/10.1186/s12915-023-01609-y

Similar Items