A novel peptide derived from human apolipoprotein E is an inhibitor of tumor growth and ocular angiogenesis.

Angiogenesis is a hallmark of tumor development and metastasis and now a validated target for cancer treatment. We previously reported that a novel dimer peptide (apoEdp) derived from the receptor binding region of human apolipoprotein E (apoE) inhibits virus-induced angiogenesis. However, its role...

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Bibliographic Details
Main Authors: Partha S Bhattacharjee, Tashfin S Huq, Tarun K Mandal, Richard A Graves, Syed Muniruzzaman, Christian Clement, Harris E McFerrin, James M Hill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21253017/?tool=EBI