The neuroblast and angioblast chemotaxic factor SDF-1 (CXCL12) expression is briefly up regulated by reactive astrocytes in brain following neonatal hypoxic-ischemic injury

<p>Abstract</p> <p>Background</p> <p>Stromal cell-derived factor 1 (SDF-1 or CXCL12) is chemotaxic for CXCR4 expressing bone marrow-derived cells. It functions in brain embryonic development and in response to ischemic injury in helping guide neuroblast migration and va...

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Bibliographic Details
Main Authors: Walker Aisha L, Wimborne Hereward JC, Bartley John H, Miller Jason T, Hess David C, Hill William D, Carroll James E
Format: Article
Language:English
Published: BMC 2005-10-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/6/63