Evidence for Rho-dependent control of a virulence switch in Acinetobacter baumannii

Evidence for Rho-dependent control of a virulence switch in Acinetobacter baumannii

ABSTRACTAcinetobacter baumannii strain AB5075 is able to interconvert at high frequency between virulent cells that form opaque colonies (VIR-O) and avirulent cells that form translucent colonies (AV-T). Cells switch from the VIR-O to the AV-T state by the combinatorial activation of at least three...

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Bibliographic Details
Main Authors: María Pérez-Varela, Raja Singh, Jennifer M. Colquhoun, Olivia G. Starich, Aimee R. P. Tierney, Kyle A. Tipton, Philip N. Rather
Format: Article
Language:English
Published: American Society for Microbiology 2024-01-01
Series:mBio
Subjects:
Acinetobacter baumannii
phenotypic heterogeneity
TetR regulator transcriptional regulator
Rho-dependent termination
Online Access:https://journals.asm.org/doi/10.1128/mbio.02708-23

Internet

https://journals.asm.org/doi/10.1128/mbio.02708-23

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