Differential effects of the LncRNA RNF157-AS1 on epithelial ovarian cancer cells through suppression of DIRAS3- and ULK1-mediated autophagy

Abstract Analyses of several databases showed that the lncRNA RNF157 Antisense RNA 1 (RNF157-AS1) is overexpressed in epithelial ovarian cancer (EOC) tissues. In our study, suppressing RNF157-AS1 strikingly reduced the proliferation, invasion, and migration of EOC cells compared with control cells,...

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Bibliographic Details
Main Authors: Pengfei Xu, Sujuan Xu, Haiyue Pan, Chencheng Dai, Yiran Xu, Luyao Wang, Yu Cong, Huilin Zhang, Jian Cao, Lili Ge, Xuemei Jia
Format: Article
Language:English
Published: Nature Publishing Group 2023-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05668-5