The Pharmacokinetics of Medetomidine Administered Subcutaneously during Isoflurane Anaesthesia in Sprague-Dawley Rats
Anaesthetic protocols involving the combined use of a sedative agent, medetomidine, and an anaesthetic agent, isoflurane, are increasingly being used in functional magnetic resonance imaging (fMRI) studies of the rodent brain. Despite the popularity of this combination, a standardised protocol for t...
Main Authors: | Leila T. Kint, Bhedita J. Seewoo, Timothy H. Hyndman, Michael W. Clarke, Scott H. Edwards, Jennifer Rodger, Kirk W. Feindel, Gabrielle C. Musk |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-06-01
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Series: | Animals |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-2615/10/6/1050 |
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