Design and validation of a disease network of inflammatory processes in the NSG-UC mouse model

Design and validation of a disease network of inflammatory processes in the NSG-UC mouse model

Abstract Background Ulcerative colitis (UC) is a highly progressive inflammatory disease that requires the interaction of epithelial, immune, endothelial and muscle cells and fibroblasts. Previous studies suggested two inflammatory conditions in UC-patients: ‘acute’ and ‘remodeling’ and that the des...

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Bibliographic Details
Main Authors: Henrika Jodeleit, Pia Palamides, Florian Beigel, Thomas Mueller, Eckhard Wolf, Matthias Siebeck, Roswitha Gropp
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Journal of Translational Medicine
Subjects:
Ulcerative colitis
Disease network
Autoimmunity
Inflammatory bowel disease
NSG
NSG-UC
Online Access:http://link.springer.com/article/10.1186/s12967-017-1368-4

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http://link.springer.com/article/10.1186/s12967-017-1368-4

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