Innate Immune Responses and P. falciparum CS Repeat-Specific Neutralizing Antibodies Following Vaccination by Skin Scarification

Innate Immune Responses and P. falciparum CS Repeat-Specific Neutralizing Antibodies Following Vaccination by Skin Scarification

The skin is the site of host invasion by the mosquito-borne Plasmodium parasite, which caused an estimated 229 million infections and 409,000 deaths in 2019 according to WHO World Malaria report 2020. In our previous studies, we have shown that skin scarification (SS) with a P. falciparum circumspor...

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Bibliographic Details
Main Authors: Robert A. Mitchell, Rita Altszuler, Sandra Gonzalez, Roshawn Johnson, Ute Frevert, Elizabeth Nardin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
Plasmodium falciparum
circumsporozoite protein
peptide
skin scarification
Toll-Like Receptor (TLR) agonist adjuvants
innate immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.801111/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.801111/full

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