An esophagus cell atlas reveals dynamic rewiring during active eosinophilic esophagitis and remission

An esophagus cell atlas reveals dynamic rewiring during active eosinophilic esophagitis and remission

Abstract Coordinated cell interactions within the esophagus maintain homeostasis, and disruption can lead to eosinophilic esophagitis (EoE), a chronic inflammatory disease with poorly understood pathogenesis. We profile 421,312 individual cells from the esophageal mucosa of 7 healthy and 15 EoE part...

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Bibliographic Details
Main Authors: Jiarui Ding, John J. Garber, Amiko Uchida, Ariel Lefkovith, Grace T. Carter, Praveen Vimalathas, Lauren Canha, Michael Dougan, Kyle Staller, Joseph Yarze, Toni M. Delorey, Orit Rozenblatt-Rosen, Orr Ashenberg, Daniel B. Graham, Jacques Deguine, Aviv Regev, Ramnik J. Xavier
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-47647-0

Internet

https://doi.org/10.1038/s41467-024-47647-0

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