Serum Free Light Chains in Common Variable Immunodeficiency Disorders: Role in Differential Diagnosis and Association With Clinical Phenotype

Serum Free Light Chains in Common Variable Immunodeficiency Disorders: Role in Differential Diagnosis and Association With Clinical Phenotype

We report on an observational, multicenter study of 345 adult CVID patients, designed to assess the diagnostic value and the clinical association of serum free light chain (sFLC) pattern in Common Variable Immunodeficiency disorders (CVID). Sixty CVID patients were tested twice in order to assess in...

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Bibliographic Details
Main Authors: Riccardo Scarpa, Federica Pulvirenti, Antonio Pecoraro, Alessandra Vultaggio, Carolina Marasco, Roberto Ria, Sara Altinier, Nicolò Compagno, Davide Firinu, Mario Plebani, Marco De Carli, Andrea Matucci, Fabrizio Vianello, Angelo Vacca, Giuseppe Spadaro, Isabella Quinti, Carlo Agostini, Cinzia Milito, Francesco Cinetto
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
serum free light chains
common variable immunodeficiency disorders (CVID)
lymphoproliferative disease (LPD)
diagnostic marker
immunoglobulin
clinical phenotype
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00319/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00319/full

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