Refined expression quantitative trait locus analysis on adenocarcinoma at the gastroesophageal junction reveals susceptibility and prognostic markers

Refined expression quantitative trait locus analysis on adenocarcinoma at the gastroesophageal junction reveals susceptibility and prognostic markers

Objectives: This study aimed to explore cell type level expression quantitative trait loci (eQTL) in adenocarcinoma at the gastroesophageal junction (ACGEJ) and identify susceptibility and prognosis markers.Methods: Whole-genome sequencing (WGS) was performed on 120 paired samples from Chinese ACGEJ...

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Bibliographic Details
Main Authors: Ce Zhong, Chen Wu, Yuan Lin, Dongxin Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Genetics
Subjects:
adenocarcinoma at the gastroesophageal junction
cell deconvolution
cell type–specific expression quantitative trait loci
linear mixed model
susceptibility biomarkers
prognostic prediction
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1180500/full

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https://www.frontiersin.org/articles/10.3389/fgene.2023.1180500/full

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