Efficient production of inhibitor-free foamy virus glycoprotein-containing retroviral vectors by proteoglycan-deficient packaging cells

Efficient production of inhibitor-free foamy virus glycoprotein-containing retroviral vectors by proteoglycan-deficient packaging cells

Foamy viruses (FVs) or heterologous retroviruses pseudotyped with FV glycoprotein enable transduction of a great variety of target tissues of disparate species. Specific cellular entry receptors responsible for this exceptionally broad tropism await their identification. Though, ubiquitously express...

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Bibliographic Details
Main Authors: Clara Marie Munz, Henriette Kreher, Alexander Erdbeer, Stefanie Richter, Dana Westphal, Buqing Yi, Rayk Behrendt, Nicole Stanke, Fabian Lindel, Dirk Lindemann
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
retrovirus
spumavirus
foamy virus
retroviral vector
pseudotyping
viral glycoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050122000961

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http://www.sciencedirect.com/science/article/pii/S2329050122000961

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