Cathepsin H Knockdown Reverses Radioresistance of Hepatocellular Carcinoma via Metabolic Switch Followed by Apoptosis

Cathepsin H Knockdown Reverses Radioresistance of Hepatocellular Carcinoma via Metabolic Switch Followed by Apoptosis

Despite the wide application of radiotherapy in HCC, radiotherapy efficacy is sometimes limited due to radioresistance. Although radioresistance is reported with high glycolysis, the underlying mechanism between radioresistance and cancer metabolism, as well as the role of cathepsin H (CTSH) within...

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Bibliographic Details
Main Authors: Qiao Chen, Shugen Qu, Zhenzhen Liang, Yi Liu, Huajian Chen, Shumei Ma, Xiaodong Liu
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
hepatocellular carcinoma
radioresistance
glycolysis
aerobic respiration
apoptosis
radiotherapy
Online Access:https://www.mdpi.com/1422-0067/24/6/5257

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https://www.mdpi.com/1422-0067/24/6/5257

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