Experimental Characterization of the Hepatitis B Virus Capsid Dynamics by Solid-State NMR

Experimental Characterization of the Hepatitis B Virus Capsid Dynamics by Solid-State NMR

Protein plasticity and dynamics are important aspects of their function. Here we use solid-state NMR to experimentally characterize the dynamics of the 3.5 MDa hepatitis B virus (HBV) capsid, assembled from  240 copies of the Cp149 core protein. We measure both T1 and T1ρ relaxation times, which we...

Full description

Bibliographic Details
Main Authors: Alexander A. Malär, Morgane Callon, Albert A. Smith, Shishan Wang, Lauriane Lecoq, Carolina Pérez-Segura, Jodi A. Hadden-Perilla, Anja Böckmann, Beat H. Meier
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
solid-state NMR
virus
dynamics
relaxation
molecular dynamics
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.807577/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.807577/full

Similar Items