Macrophage Plasticity and Polarization Are Altered in the Experimental Model of Multiple Sclerosis

Macrophage Plasticity and Polarization Are Altered in the Experimental Model of Multiple Sclerosis

Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system. MS is characterized by infiltrations of leukocytes such as T and B lymphocytes and macrophages. Macrophages have been identified as major effectors of inflammation and demyelination in both MS and its...

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Bibliographic Details
Main Authors: Alessandro Leuti, Emanuela Talamonti, Antonietta Gentile, Marta Tiberi, Alessandro Matteocci, Diego Fresegna, Diego Centonze, Valerio Chiurchiù
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomolecules
Subjects:
multiple sclerosis
EAE
macrophages
cytokines
chemokines
toll-like receptors
Online Access:https://www.mdpi.com/2218-273X/11/6/837

Internet

https://www.mdpi.com/2218-273X/11/6/837

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